Entrectinib: A new TKI for ROS1+ NSCLC with brain mets
I’m embarrassed that I’ve had this article open in my browser for months and haven’t written about it. Good news for ROS1nders! Entrectinib is getting close to FDA approval. While…
I’m embarrassed that I’ve had this article open in my browser for months and haven’t written about it. Good news for ROS1nders! Entrectinib is getting close to FDA approval. While…
Five weeks in and the side effects I’m experiencing from lorlatinib are so much better than those I experienced on crizotinib: Tiny negative impact to my memory and attention. Continued…
This one is good. My lorlatinib instructions are to take 4 25mg tablets once per day. I thought that was weird since I know they make a 100mg tablet. What’s…
Today is my seventh day taking lorlatinib and my fourth day back at work. I could have returned to work earlier but Good Friday and Easter Monday are public holidays…
I spent three days on the road with less than a 12-hour turnaround in Austin and arrived home last night with a month’s worth of lorlatinib. Victory! I took my…
Here’s where I am in the mad dash to find the next treatment for my quickly growing brain tumors: Plan A: Lorlatinib Trial in Boston The advantage here is free…
It’s not really a surprise since I can see and feel my tumors grow, but my oncologist confirmed today that I’ve officially had progression while on crizotinib. I’ve developed resistance.…
I was pretty nervous about our whirlwind trip through the US. Seattle, Albuquerque, Austin, Minnesota, Baltimore, New York, and Austin again was a pretty punishing schedule given how I was…
Brad and I have spent the past couple of days mulling over the advice of the oncology team at they Mayo Clinic to stop taking crizotinib and move to lorlatinib.…
I just wrapped up two consecutive ten hours days at the Mayo Clinic. I’ll post an update about the entire carnival of medicine later but for now here are the…
I really can’t believe how lucky I am that my cancer has so many well-researched genetic mutations. With the number of treatments targeting these alterations, I sincerely believe that cancer…
Recovery from the brain radiation was a little slow but I’m just about there. I’m still sleeping a lot but have started weaning myself off the anti-vomiting meds. I’d ordered…
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